Combination of ozone and mesenchimal cells to repair the intervertebral disc [abstract]
نویسندگان
چکیده
منابع مشابه
incidence of microscopic lumbar intervertebral disc calcification and its correlation to endplate degeneration type and disc histopathologic angiogensis
چکیده ندارد.
15 صفحه اولThe Promise of Mesenchymal Stem Cells for Intervertebral Disc Repair
Disc degeneration (DD) is a major musculoskeletal condition affecting 80% of the general global population [1]. The associated low back pain (LBP) has major socioeconomic impact reviewed in [2]. In the past 25 years a number of promising biological therapies have been investigated for the treatment of degenerative Disc Disease (DDD) and these have identified many potential molecular targets for...
متن کاملMesenchymal stem cells reduce intervertebral disc fibrosis and facilitate repair.
Intervertebral disc degeneration is associated with back pain and radiculopathy which, being a leading cause of disability, seriously affects the quality of life and presents a hefty burden to society. There is no effective intervention for the disease and the etiology remains unclear. Here, we show that disc degeneration exhibits features of fibrosis in humans and confirmed this in a puncture-...
متن کاملMesenchymal stem cells for intervertebral disc repair and regeneration
Low back pain secondary to degenerative intervertebral disc disease contributes to significant pain and disability in the United States. The potential to reverse intervertebral disc degeneration has driven significant interest in the development of stem cell therapy for degenerative disc disease. Early animal models have demonstrated that stem cell therapy may facilitate the reversal of the dis...
متن کاملEffects of Morphine Dependency on Intervertebral Disc in the Rat
Background: A large proportion of patients presenting with lumbar disc disease are opium addicts in our region. It was, therefore, hypothesized that morphine might affect the intervertebral disc. We investigated the histological findings of morphine dependency on intervertebral discs in rat. Methods: Forty NMRI adult male rats (230-250 g) placed on ordinary diet and received aqueous solution of...
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ژورنال
عنوان ژورنال: Journal of Ozone Therapy
سال: 2019
ISSN: 2444-9865
DOI: 10.7203/jo3t.3.4.2019.15504